Protecting shared drives from viruses?

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i'm trying figure out if there way make programs can change files of shared network drive. have software dependent on shared drives (no way around them) have been hit multiple times crypto locker virus. of our workstations have vipre business virus protection , email protection , our email hosted office 365, virus still able on our network thru email. i've seen disable vipre. have software not work unless user administrator on workstation. have setup group policy rules not allow programs run in general places virus likes run, i'm sure not stop forever. if our accounting software drive gets hit major headache. so, able setup rule on workstation or in group policy says programs can make changes files on shared network drive, no other programs can. know if possible? 

hi,

permissions in windows based on users, not programs. cannot setup rule programs can make changes files on shared network drive. in case, drive infected cryptolocker, need backup drive periodically. if drive encrypted, restore encrypted files. 

regards,

mandy

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